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Age-Dependent TLR3 Expression of the Intestinal Epithelium Contributes to Rotavirus Susceptibility

Rotavirus is a major cause of diarrhea worldwide and exhibits a pronounced small intestinal epithelial cell (IEC) tropism. Both human infants and neonatal mice are highly susceptible, whereas adult individuals remain asymptomatic and shed only low numbers of viral particles. Here we investigated age...

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Detalles Bibliográficos
Autores principales:	Pott, Johanna, Stockinger, Silvia, Torow, Natalia, Smoczek, Anna, Lindner, Cornelia, McInerney, Gerald, Bäckhed, Fredrik, Baumann, Ulrich, Pabst, Oliver, Bleich, André, Hornef, Mathias W.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3343008/ https://www.ncbi.nlm.nih.gov/pubmed/22570612 http://dx.doi.org/10.1371/journal.ppat.1002670

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