Upregulation of the Wnt Co-Receptor LRP6 Promotes Hepatocarcinogenesis and Enhances Cell Invasion

BACKGROUND: Activation of the Wnt/β-catenin signaling pathway plays a crucial role in hepatocellular carcinoma (HCC). Low-density lipoprotein (LDL) receptor-related protein-6 (LRP6) is one of the co-receptors of the Wnt/β-catenin pathway and forms a signaling complex with Wnt ligand and Frizzled rec...

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Detalles Bibliográficos
Autores principales: Tung, Edmund Kwok-Kwan, Wong, Betty Yin-Chi, Yau, Tai-On, Ng, Irene Oi-Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3343020/
https://www.ncbi.nlm.nih.gov/pubmed/22570728
http://dx.doi.org/10.1371/journal.pone.0036565

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3343020/
https://www.ncbi.nlm.nih.gov/pubmed/22570728
http://dx.doi.org/10.1371/journal.pone.0036565

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