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The Homeodomain-Containing Transcription Factors Arx and Pax4 Control Enteroendocrine Subtype Specification in Mice

Intestinal hormones are key regulators of digestion and energy homeostasis secreted by rare enteroendocrine cells. These cells produce over ten different hormones including GLP-1 and GIP peptides known to promote insulin secretion. To date, the molecular mechanisms controlling the specification of t...

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Detalles Bibliográficos
Autores principales: Beucher, Anthony, Gjernes, Elisabet, Collin, Caitlin, Courtney, Monica, Meunier, Aline, Collombat, Patrick, Gradwohl, Gérard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3343025/
https://www.ncbi.nlm.nih.gov/pubmed/22570716
http://dx.doi.org/10.1371/journal.pone.0036449