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Co-Stimulation of PAFR and CD36 Is Required for oxLDL-Induced Human Macrophages Activation
The oxidative process of LDL particles generates molecules which are structurally similar to platelet-activating factor (PAF), and some effects of oxidized LDL (oxLDL) have been shown to be dependent on PAF receptor (PAFR) activation. In a previous study, we showed that PAFR is required for upregula...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3343035/ https://www.ncbi.nlm.nih.gov/pubmed/22570732 http://dx.doi.org/10.1371/journal.pone.0036632 |