Immunological Tolerance to Muscle Autoantigens Involves Peripheral Deletion of Autoreactive CD8(+) T Cells

Muscle potentially represents the most abundant source of autoantigens of the body and can be targeted by a variety of severe autoimmune diseases. Yet, the mechanisms of immunological tolerance toward muscle autoantigens remain mostly unknown. We investigated this issue in transgenic SM-Ova mice tha...

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Detalles Bibliográficos
Autores principales: Franck, Emilie, Bonneau, Carole, Jean, Laetitia, Henry, Jean-Paul, Lacoume, Yann, Salvetti, Anna, Boyer, Olivier, Adriouch, Sahil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3343038/
https://www.ncbi.nlm.nih.gov/pubmed/22570714
http://dx.doi.org/10.1371/journal.pone.0036444

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3343038/
https://www.ncbi.nlm.nih.gov/pubmed/22570714
http://dx.doi.org/10.1371/journal.pone.0036444

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