Influenza Polymerase Activity Correlates with the Strength of Interaction between Nucleoprotein and PB2 through the Host-Specific Residue K/E627

The ribonucleoprotein (RNP) complex is the essential transcription-replication machinery of the influenza virus. It is composed of the trimeric polymerase (PA, PB1 and PB2), nucleoprotein (NP) and RNA. Elucidating the molecular mechanisms of RNP assembly is central to our understanding of the contro...

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Detalles Bibliográficos
Autores principales: Ng, Andy Ka-Leung, Chan, Wai-Hon, Choi, Sze-Ting, Lam, Mandy Ka-Han, Lau, Kwok-Fai, Chan, Paul Kay-Sheung, Au, Shannon Wing-Ngor, Fodor, Ervin, Shaw, Pang-Chui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3343083/
https://www.ncbi.nlm.nih.gov/pubmed/22570712
http://dx.doi.org/10.1371/journal.pone.0036415

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3343083/
https://www.ncbi.nlm.nih.gov/pubmed/22570712
http://dx.doi.org/10.1371/journal.pone.0036415

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