Exploring the Contextual Sensitivity of Factors that Determine Cell-to-Cell Variability in Receptor-Mediated Apoptosis

Stochastic fluctuations in gene expression give rise to cell-to-cell variability in protein levels which can potentially cause variability in cellular phenotype. For TRAIL (TNF-related apoptosis-inducing ligand) variability manifests itself as dramatic differences in the time between ligand exposure...

Descripción completa

Detalles Bibliográficos
Autores principales: Gaudet, Suzanne, Spencer, Sabrina L., Chen, William W., Sorger, Peter K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3343095/
https://www.ncbi.nlm.nih.gov/pubmed/22570596
http://dx.doi.org/10.1371/journal.pcbi.1002482

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3343095/
https://www.ncbi.nlm.nih.gov/pubmed/22570596
http://dx.doi.org/10.1371/journal.pcbi.1002482

Ejemplares similares