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Testing Biochemistry Revisited: How In Vivo Metabolism Can Be Understood from In Vitro Enzyme Kinetics

A decade ago, a team of biochemists including two of us, modeled yeast glycolysis and showed that one of the most studied biochemical pathways could not be quite understood in terms of the kinetic properties of the constituent enzymes as measured in cell extract. Moreover, when the same model was la...

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Detalles Bibliográficos
Autores principales: van Eunen, Karen, Kiewiet, José A. L., Westerhoff, Hans V., Bakker, Barbara M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3343101/
https://www.ncbi.nlm.nih.gov/pubmed/22570597
http://dx.doi.org/10.1371/journal.pcbi.1002483