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Testing Biochemistry Revisited: How In Vivo Metabolism Can Be Understood from In Vitro Enzyme Kinetics
A decade ago, a team of biochemists including two of us, modeled yeast glycolysis and showed that one of the most studied biochemical pathways could not be quite understood in terms of the kinetic properties of the constituent enzymes as measured in cell extract. Moreover, when the same model was la...
Autores principales: | van Eunen, Karen, Kiewiet, José A. L., Westerhoff, Hans V., Bakker, Barbara M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3343101/ https://www.ncbi.nlm.nih.gov/pubmed/22570597 http://dx.doi.org/10.1371/journal.pcbi.1002483 |
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