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Theoretical Analysis of Competing Conformational Transitions in Superhelical DNA

We develop a statistical mechanical model to analyze the competitive behavior of transitions to multiple alternate conformations in a negatively supercoiled DNA molecule of kilobase length and specified base sequence. Since DNA superhelicity topologically couples together the transition behaviors of...

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Detalles Bibliográficos
Autores principales: Zhabinskaya, Dina, Benham, Craig J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3343103/
https://www.ncbi.nlm.nih.gov/pubmed/22570598
http://dx.doi.org/10.1371/journal.pcbi.1002484