Genetic Inhibition of Solute-Linked Carrier 39 Family Transporter 1 Ameliorates Aβ Pathology in a Drosophila Model of Alzheimer's Disease

The aggregation or oligomerization of amyloid-β (Aβ) peptide is thought to be the primary causative event in the pathogenesis of Alzheimer's disease (AD). Considerable in vitro evidence indicates that the aggregation/oligomerization of Aβ is promoted in the presence of Zn; however, the function...

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Detalles Bibliográficos
Autores principales: Lang, Minglin, Wang, Lei, Fan, Qiangwang, Xiao, Guiran, Wang, Xiaoxi, Zhong, Yi, Zhou, Bing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3343105/
https://www.ncbi.nlm.nih.gov/pubmed/22570624
http://dx.doi.org/10.1371/journal.pgen.1002683

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3343105/
https://www.ncbi.nlm.nih.gov/pubmed/22570624
http://dx.doi.org/10.1371/journal.pgen.1002683

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