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Microarray Analysis of LTR Retrotransposon Silencing Identifies Hdac1 as a Regulator of Retrotransposon Expression in Mouse Embryonic Stem Cells

Retrotransposons are highly prevalent in mammalian genomes due to their ability to amplify in pluripotent cells or developing germ cells. Host mechanisms that silence retrotransposons in germ cells and pluripotent cells are important for limiting the accumulation of the repetitive elements in the ge...

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Detalles Bibliográficos
Autores principales: Reichmann, Judith, Crichton, James H., Madej, Monika J., Taggart, Mary, Gautier, Philippe, Garcia-Perez, Jose Luis, Meehan, Richard R., Adams, Ian R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3343110/
https://www.ncbi.nlm.nih.gov/pubmed/22570599
http://dx.doi.org/10.1371/journal.pcbi.1002486