A Novel Small Molecule Inhibitor of Influenza A Viruses that Targets Polymerase Function and Indirectly Induces Interferon

Influenza viruses continue to pose a major public health threat worldwide and options for antiviral therapy are limited by the emergence of drug-resistant virus strains. The antiviral cytokine, interferon (IFN) is an essential mediator of the innate immune response and influenza viruses, like many v...

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Detalles Bibliográficos
Autores principales: Ortigoza, Mila Brum, Dibben, Oliver, Maamary, Jad, Martinez-Gil, Luis, Leyva-Grado, Victor H., Abreu, Pablo, Ayllon, Juan, Palese, Peter, Shaw, Megan L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3343121/
https://www.ncbi.nlm.nih.gov/pubmed/22577360
http://dx.doi.org/10.1371/journal.ppat.1002668

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3343121/
https://www.ncbi.nlm.nih.gov/pubmed/22577360
http://dx.doi.org/10.1371/journal.ppat.1002668

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