A mouse model of vitiligo with focused epidermal depigmentation requires IFN-γ for autoreactive CD8(+) T cell accumulation in the skin

Vitiligo is an autoimmune disease of the skin causing disfiguring patchy depigmentation of the epidermis and, less commonly, hair. Therapeutic options for vitiligo are limited, reflecting in part limited knowledge of disease pathogenesis. Existing mouse models of vitiligo consist of hair depigmentat...

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Detalles Bibliográficos
Autores principales: Harris, John E., Harris, Tajie H., Weninger, Wolfgang, Wherry, E. John, Hunter, Christopher A., Turka, Laurence A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3343174/
https://www.ncbi.nlm.nih.gov/pubmed/22297636
http://dx.doi.org/10.1038/jid.2011.463

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3343174/
https://www.ncbi.nlm.nih.gov/pubmed/22297636
http://dx.doi.org/10.1038/jid.2011.463

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