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A mouse model of vitiligo with focused epidermal depigmentation requires IFN-γ for autoreactive CD8(+) T cell accumulation in the skin
Vitiligo is an autoimmune disease of the skin causing disfiguring patchy depigmentation of the epidermis and, less commonly, hair. Therapeutic options for vitiligo are limited, reflecting in part limited knowledge of disease pathogenesis. Existing mouse models of vitiligo consist of hair depigmentat...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3343174/ https://www.ncbi.nlm.nih.gov/pubmed/22297636 http://dx.doi.org/10.1038/jid.2011.463 |