Acquired cancer stem cell phenotypes through Oct4-mediated dedifferentiation

There is enormous interest to target cancer stem cells (CSCs) for clinical treatment because these cells are highly tumorigenic and resistant to chemotherapy. Oct4 is expressed by CSC-like cells in different types of cancer. However, function of Oct4 in tumor cells is unclear. In this study, we show...

Descripción completa

Detalles Bibliográficos
Autores principales: Kumar, Suresh M., Liu, Shujing, Lu, Hezhe, Zhang, Hongtao, Zhang, Paul J., Gimotty, Phyllis A., Guerra, Matthew, Guo, Wei, Xu, Xiaowei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3343184/
https://www.ncbi.nlm.nih.gov/pubmed/22286766
http://dx.doi.org/10.1038/onc.2011.656

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3343184/
https://www.ncbi.nlm.nih.gov/pubmed/22286766
http://dx.doi.org/10.1038/onc.2011.656

Ejemplares similares