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Acquired cancer stem cell phenotypes through Oct4-mediated dedifferentiation

There is enormous interest to target cancer stem cells (CSCs) for clinical treatment because these cells are highly tumorigenic and resistant to chemotherapy. Oct4 is expressed by CSC-like cells in different types of cancer. However, function of Oct4 in tumor cells is unclear. In this study, we show...

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Detalles Bibliográficos
Autores principales:	Kumar, Suresh M., Liu, Shujing, Lu, Hezhe, Zhang, Hongtao, Zhang, Paul J., Gimotty, Phyllis A., Guerra, Matthew, Guo, Wei, Xu, Xiaowei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2012
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3343184/ https://www.ncbi.nlm.nih.gov/pubmed/22286766 http://dx.doi.org/10.1038/onc.2011.656

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