Anti-DNA auto-antibodies initiate experimental lupus nephritis by binding directly to the glomerular basement membrane in mice

The strongest serological correlate for lupus nephritis is antibody to double-stranded DNA although the mechanism by which anti-DNA antibodies initiate lupus nephritis is unresolved. Most recent reports indicate that anti-DNA must bind chromatin in the glomerular basement membrane or mesangial matri...

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Detalles Bibliográficos
Autores principales: Krishnan, Meera R., Wang, Congmiao, Marion, Tony N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3343188/
https://www.ncbi.nlm.nih.gov/pubmed/22297676
http://dx.doi.org/10.1038/ki.2011.484

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3343188/
https://www.ncbi.nlm.nih.gov/pubmed/22297676
http://dx.doi.org/10.1038/ki.2011.484

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