Cargando…

Deletion of scavenger receptor A protects mice from progressive nephropathy independent of lipid control during diet-induced hyperlipidemia

Scavenger receptor A (SR-A) is a key transmembrane receptor in the endocytosis of lipids and contributes to the pathogenesis of atherosclerosis. To assess its role in hyperlipidemic chronic kidney disease, wild-type and SR-A-deficient (knockout) mice underwent uninephrectomy followed by either norma...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Wenjian, He, Bin, Shi, Wei, Liang, Xinling, Ma, Jianchao, Shan, Zhixin, Hu, Zhaoyong, Danesh, Farhad R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3343314/
https://www.ncbi.nlm.nih.gov/pubmed/22377830
http://dx.doi.org/10.1038/ki.2011.457