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Deletion of scavenger receptor A protects mice from progressive nephropathy independent of lipid control during diet-induced hyperlipidemia
Scavenger receptor A (SR-A) is a key transmembrane receptor in the endocytosis of lipids and contributes to the pathogenesis of atherosclerosis. To assess its role in hyperlipidemic chronic kidney disease, wild-type and SR-A-deficient (knockout) mice underwent uninephrectomy followed by either norma...
Autores principales: | Wang, Wenjian, He, Bin, Shi, Wei, Liang, Xinling, Ma, Jianchao, Shan, Zhixin, Hu, Zhaoyong, Danesh, Farhad R |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3343314/ https://www.ncbi.nlm.nih.gov/pubmed/22377830 http://dx.doi.org/10.1038/ki.2011.457 |
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