Inorganic polyphosphate is a potent activator of the mitochondrial permeability transition pore in cardiac myocytes

Mitochondrial dysfunction caused by excessive Ca(2+) accumulation is a major contributor to cardiac cell and tissue damage during myocardial infarction and ischemia–reperfusion injury (IRI). At the molecular level, mitochondrial dysfunction is induced by Ca(2+)-dependent opening of the mitochondrial...

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Detalles Bibliográficos
Autores principales: Seidlmayer, Lea K., Gomez-Garcia, Maria R., Blatter, Lothar A., Pavlov, Evgeny, Dedkova, Elena N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3343371/
https://www.ncbi.nlm.nih.gov/pubmed/22547663
http://dx.doi.org/10.1085/jgp.201210788

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3343371/
https://www.ncbi.nlm.nih.gov/pubmed/22547663
http://dx.doi.org/10.1085/jgp.201210788

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