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Identification of a novel post-hydrolytic state in CFTR gating

Adenosine triphosphate (ATP)-binding cassette (ABC) transporters, ubiquitous proteins found in all kingdoms of life, catalyze substrates translocation across biological membranes using the free energy of ATP hydrolysis. Cystic fibrosis transmembrane conductance regulator (CFTR) is a unique member of...

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Detalles Bibliográficos
Autores principales: Jih, Kang-Yang, Sohma, Yoshiro, Li, Min, Hwang, Tzyh-Chang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3343372/
https://www.ncbi.nlm.nih.gov/pubmed/22508846
http://dx.doi.org/10.1085/jgp.201210789