Gating properties of the P2X2a and P2X2b receptor channels: Experiments and mathematical modeling

Adenosine triphosphate (ATP)-gated P2X2 receptors exhibit two opposite activation-dependent changes, pore dilation and pore closing (desensitization), through a process that is incompletely understood. To address this issue and to clarify the roles of calcium and the C-terminal domain in gating, we...

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Detalles Bibliográficos
Autores principales: Khadra, Anmar, Yan, Zonghe, Coddou, Claudio, Tomić, Melanija, Sherman, Arthur, Stojilkovic, Stanko S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3343373/
https://www.ncbi.nlm.nih.gov/pubmed/22547664
http://dx.doi.org/10.1085/jgp.201110716

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3343373/
https://www.ncbi.nlm.nih.gov/pubmed/22547664
http://dx.doi.org/10.1085/jgp.201110716

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