Cargando…
The intrinsic energy of the gating isomerization of a neuromuscular acetylcholine receptor channel
Nicotinic acetylcholine receptor (AChR) channels at neuromuscular synapses rarely open in the absence of agonists, but many different mutations increase the unliganded gating equilibrium constant (E(0)) to generate AChRs that are active constitutively. We measured E(0) for two different sets of muta...
| Autores principales: | , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2012
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3343375/ https://www.ncbi.nlm.nih.gov/pubmed/22547665 http://dx.doi.org/10.1085/jgp.201110752 |