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Computational Insights into Binding of Bisphosphates to Farnesyl Pyrophosphate Synthase

Bisphosphonates (BPs) are the most widely used and effective treatment for osteoporosis and Paget's disease. Non-nitrogen containing BPs (non-N-BPs), namely etidronate, clodronate, tiludronate, as well as nitrogen-containing BPs (N-BPs), namely pamidronate, alendronate, ibandronate, risedronate...

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Detalles Bibliográficos
Autores principales: Ohno, K, Mori, K, Orita, M, Takeuchi, M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bentham Science Publishers Ltd 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3343387/
https://www.ncbi.nlm.nih.gov/pubmed/21110804
http://dx.doi.org/10.2174/092986711794088335