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Effects of acutely inhibiting PI3K isoforms and mTOR on regulation of glucose metabolism in vivo

In in vitro studies class-I PI3Ks (phosphoinositide 3-kinases), class-II PI3Ks and mTOR (mammalian target of rapamycin) have all been described as having roles in the regulation of glucose metabolism. The relative role each plays in the normal signalling processes regulating glucose metabolism in vi...

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Detalles Bibliográficos
Autores principales: Smith, Greg C., Ong, Wee Kiat, Rewcastle, Gordon W., Kendall, Jackie D., Han, Weiping, Shepherd, Peter R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3343648/
https://www.ncbi.nlm.nih.gov/pubmed/22142257
http://dx.doi.org/10.1042/BJ20111913