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Total Synthesis of a Cyclic Adenosine 5′-Diphosphate Ribose Receptor Agonist

[Image: see text] Stable cyclic adenosine 5′-diphosphate ribose (cADPR) analogues are chemical biology tools that can probe the Ca(2+) release mechanism and structure–activity relationships of this emerging potent second messenger. However, analogues with an intact “northern” ribose have been inacce...

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Detalles Bibliográficos
Autores principales: Swarbrick, Joanna M., Potter, Barry V. L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2012
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3343700/
https://www.ncbi.nlm.nih.gov/pubmed/22283398
http://dx.doi.org/10.1021/jo202319f