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Heme Cytotoxicity and the Pathogenesis of Immune-Mediated Inflammatory Diseases

Heme, iron (Fe) protoporphyrin IX, functions as a prosthetic group in a range of hemoproteins essential to support life under aerobic conditions. The Fe contained within the prosthetic heme groups of these hemoproteins can catalyze the production of reactive oxygen species. Presumably for this reaso...

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Detalles Bibliográficos
Autores principales: Larsen, Rasmus, Gouveia, Zélia, Soares, Miguel P., Gozzelino, Raffaella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Research Foundation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3343703/
https://www.ncbi.nlm.nih.gov/pubmed/22586395
http://dx.doi.org/10.3389/fphar.2012.00077