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Heme Cytotoxicity and the Pathogenesis of Immune-Mediated Inflammatory Diseases
Heme, iron (Fe) protoporphyrin IX, functions as a prosthetic group in a range of hemoproteins essential to support life under aerobic conditions. The Fe contained within the prosthetic heme groups of these hemoproteins can catalyze the production of reactive oxygen species. Presumably for this reaso...
Autores principales: | Larsen, Rasmus, Gouveia, Zélia, Soares, Miguel P., Gozzelino, Raffaella |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Research Foundation
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3343703/ https://www.ncbi.nlm.nih.gov/pubmed/22586395 http://dx.doi.org/10.3389/fphar.2012.00077 |
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