Toward the Understanding of the Metabolism of Levodopa I. DFT Investigation of the Equilibrium Geometries, Acid-Base Properties and Levodopa-Water Complexes

Levodopa (LD) is used to increase dopamine level for treating Parkinson’s disease. The major metabolism of LD to produce dopamine is decarboxylation. In order to understand the metabolism of LD; the electronic structure of levodopa was investigated at the Density Functional DFT/B3LYP level of theory...

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Detalles Bibliográficos
Autores principales: Elroby, Shabaan A. K., Makki, Mohamed S. I., Sobahi, Tariq R., Hilal, Rifaat H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3344216/
https://www.ncbi.nlm.nih.gov/pubmed/22605980
http://dx.doi.org/10.3390/ijms13044321

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3344216/
https://www.ncbi.nlm.nih.gov/pubmed/22605980
http://dx.doi.org/10.3390/ijms13044321

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