Macrophage-Stimulated Cardiac Fibroblast Production of IL-6 Is Essential for TGF β/Smad Activation and Cardiac Fibrosis Induced by Angiotensin II

Interleukin-6 (IL-6) is an important cytokine participating in multiple biologic activities in immune regulation and inflammation. IL-6 has been associated with cardiovascular remodeling. However, the mechanism of IL-6 in hypertensive cardiac fibrosis is still unclear. Angiotensin II (Ang II) infusi...

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Detalles Bibliográficos
Autores principales: Ma, Feifei, Li, Yulin, Jia, Lixin, Han, Yalei, Cheng, Jizhong, Li, Huihua, Qi, Yongfen, Du, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3344835/
https://www.ncbi.nlm.nih.gov/pubmed/22574112
http://dx.doi.org/10.1371/journal.pone.0035144

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3344835/
https://www.ncbi.nlm.nih.gov/pubmed/22574112
http://dx.doi.org/10.1371/journal.pone.0035144

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