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Extensive Translatome Remodeling during ER Stress Response in Mammalian Cells

In this work we have described the translatome of two mammalian cell lines, NIH3T3 and Jurkat, by scoring the relative polysome association of ∼10,000 mRNA under normal and ER stress conditions. We have found that translation efficiencies of mRNA correlated poorly with transcript abundance, although...

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Detalles Bibliográficos
Autores principales: Ventoso, Iván, Kochetov, Alex, Montaner, David, Dopazo, Joaquín, Santoyo, Javier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3344847/
https://www.ncbi.nlm.nih.gov/pubmed/22574127
http://dx.doi.org/10.1371/journal.pone.0035915