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Extensive Translatome Remodeling during ER Stress Response in Mammalian Cells
In this work we have described the translatome of two mammalian cell lines, NIH3T3 and Jurkat, by scoring the relative polysome association of ∼10,000 mRNA under normal and ER stress conditions. We have found that translation efficiencies of mRNA correlated poorly with transcript abundance, although...
Autores principales: | Ventoso, Iván, Kochetov, Alex, Montaner, David, Dopazo, Joaquín, Santoyo, Javier |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3344847/ https://www.ncbi.nlm.nih.gov/pubmed/22574127 http://dx.doi.org/10.1371/journal.pone.0035915 |
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