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Identification and Characterization of Antifungal Compounds Using a Saccharomyces cerevisiae Reporter Bioassay
New antifungal drugs are urgently needed due to the currently limited selection, the emergence of drug resistance, and the toxicity of several commonly used drugs. To identify drug leads, we screened small molecules using a Saccharomyces cerevisiae reporter bioassay in which S. cerevisiae heterologo...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3344848/ https://www.ncbi.nlm.nih.gov/pubmed/22574132 http://dx.doi.org/10.1371/journal.pone.0036021 |