Identification and Characterization of Antifungal Compounds Using a Saccharomyces cerevisiae Reporter Bioassay

New antifungal drugs are urgently needed due to the currently limited selection, the emergence of drug resistance, and the toxicity of several commonly used drugs. To identify drug leads, we screened small molecules using a Saccharomyces cerevisiae reporter bioassay in which S. cerevisiae heterologo...

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Detalles Bibliográficos
Autores principales: Tebbets, Brad, Stewart, Douglas, Lawry, Stephanie, Nett, Jeniel, Nantel, Andre, Andes, David, Klein, Bruce S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3344848/
https://www.ncbi.nlm.nih.gov/pubmed/22574132
http://dx.doi.org/10.1371/journal.pone.0036021

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