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Sequencing by Hybridization of Long Targets

Sequencing by Hybridization (SBH) reconstructs an n-long target DNA sequence from its biochemically determined l-long subsequences. In the standard approach, the length of a uniformly random sequence that can be unambiguously reconstructed is limited to [Image: see text] due to repetitive subsequenc...

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Detalles Bibliográficos
Autores principales: Qin, Yu, Schneider, Tobias M., Brenner, Michael P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3344849/
https://www.ncbi.nlm.nih.gov/pubmed/22574124
http://dx.doi.org/10.1371/journal.pone.0035819