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Alpha-Toxin Induces Programmed Cell Death of Human T cells, B cells, and Monocytes during USA300 Infection

This investigation examines the influence of alpha-toxin (Hla) during USA300 infection of human leukocytes. Survival of an USA300 isogenic deletion mutant of hla (USA300Δhla) in human blood was comparable to the parental wild-type strain and polymorphonuclear leukocyte (PMN) plasma membrane permeabi...

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Detalles Bibliográficos
Autores principales: Nygaard, Tyler K., Pallister, Kyler B., DuMont, Ashley L., DeWald, Mark, Watkins, Robert L., Pallister, Erik Q., Malone, Cheryl, Griffith, Shannon, Horswill, Alexander R., Torres, Victor J., Voyich, Jovanka M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3344897/
https://www.ncbi.nlm.nih.gov/pubmed/22574180
http://dx.doi.org/10.1371/journal.pone.0036532