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Conditional Wwox Deletion in Mouse Mammary Gland by Means of Two Cre Recombinase Approaches

Loss of WWOX expression has been reported in many different cancers including breast cancer. Elucidating the function of this gene in adult tissues has not been possible with full Wwox knockout models. Here we characterize the first conditional models of Wwox ablation in mouse mammary epithelium uti...

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Detalles Bibliográficos
Autores principales: Ferguson, Brent W., Gao, Xinsheng, Kil, Hyunsuk, Lee, Jaeho, Benavides, Fernando, Abba, Martin C., Aldaz, C. Marcelo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3344920/
https://www.ncbi.nlm.nih.gov/pubmed/22574198
http://dx.doi.org/10.1371/journal.pone.0036618