The Hydrogen–Deuterium Exchange at α-Carbon Atom in N,N,N-Trialkylglycine Residue: ESI-MS Studies

Derivatization of peptides as quaternary ammonium salts (QAS) is a known method for sensitive detection by electrospray ionization tandem mass spectrometry. Hydrogens at α-carbon atom in N,N,N-trialkylglycine residue can be easily exchanged by deuterons. The exchange reaction is base-catalyzed and i...

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Detalles Bibliográficos
Autores principales: Rudowska, Magdalena, Wojewska, Dominika, Kluczyk, Alicja, Bąchor, Remigiusz, Stefanowicz, Piotr, Szewczuk, Zbigniew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer-Verlag 2012
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3345113/
https://www.ncbi.nlm.nih.gov/pubmed/22403022
http://dx.doi.org/10.1007/s13361-012-0359-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3345113/
https://www.ncbi.nlm.nih.gov/pubmed/22403022
http://dx.doi.org/10.1007/s13361-012-0359-1

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