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The Hydrogen–Deuterium Exchange at α-Carbon Atom in N,N,N-Trialkylglycine Residue: ESI-MS Studies
Derivatization of peptides as quaternary ammonium salts (QAS) is a known method for sensitive detection by electrospray ionization tandem mass spectrometry. Hydrogens at α-carbon atom in N,N,N-trialkylglycine residue can be easily exchanged by deuterons. The exchange reaction is base-catalyzed and i...
Autores principales: | Rudowska, Magdalena, Wojewska, Dominika, Kluczyk, Alicja, Bąchor, Remigiusz, Stefanowicz, Piotr, Szewczuk, Zbigniew |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer-Verlag
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3345113/ https://www.ncbi.nlm.nih.gov/pubmed/22403022 http://dx.doi.org/10.1007/s13361-012-0359-1 |
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