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Antimycobacterial Activities of Novel 5-(1H-1,2,3-Triazolyl)Methyl Oxazolidinones

The antibacterial activities of a series of triazolyl oxazolidinones against Mycobacterium tuberculosis strain in vitro and in vivo in a mice model are presented. Most active compounds were noncytotoxic against VERO cells with acceptable selectivity indexes (SI) as measures of compound tolerability....

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Detalles Bibliográficos
Autores principales: Phillips, Oludotun Adebayo, Udo, Edet Ekpenyong, Varghese, Reny
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3345221/
https://www.ncbi.nlm.nih.gov/pubmed/22577542
http://dx.doi.org/10.1155/2012/289136