Nucleofection induces transient eIF2α phosphorylation by GCN2 and PERK

Nucleofection permits efficient transfection even with difficult cell types such as primary and non-dividing cells, and is used to deliver various nucleic acids including DNA, mRNA, and siRNA. Unlike DNA and siRNA, mRNA is subject to rapid degradation, which necessitates instant early translation fo...

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Detalles Bibliográficos
Autores principales: Anderson, Bart R., Karikó, Katalin, Weissman, Drew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3345295/
https://www.ncbi.nlm.nih.gov/pubmed/22301437
http://dx.doi.org/10.1038/gt.2012.5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3345295/
https://www.ncbi.nlm.nih.gov/pubmed/22301437
http://dx.doi.org/10.1038/gt.2012.5

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