Molecular mechanisms of Cys-loop ion channel receptor modulation by ivermectin

Ivermectin is an anthelmintic drug that works by inhibiting neuronal activity and muscular contractility in arthropods and nematodes. It works by activating glutamate-gated chloride channels (GluClRs) at nanomolar concentrations. These receptors, found exclusively in invertebrates, belong to the pen...

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Detalles Bibliográficos
Autores principales: Lynagh, Timothy, Lynch, Joseph W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2012
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3345530/
https://www.ncbi.nlm.nih.gov/pubmed/22586367
http://dx.doi.org/10.3389/fnmol.2012.00060

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3345530/
https://www.ncbi.nlm.nih.gov/pubmed/22586367
http://dx.doi.org/10.3389/fnmol.2012.00060

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