Role of Intrapancreatic SPINK1/Spink3 Expression in the Development of Pancreatitis

Studies on hereditary pancreatitis have provided evidence in favor of central role for trypsin activity in the disease. Identification of genetic variants of trypsinogen linked the protease to the onset of pancreatitis, and biochemical characterization proposed an enzymatic gain of function as the i...

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Detalles Bibliográficos
Autores principales: Ohmuraya, Masaki, Sugano, Aki, Hirota, Masahiko, Takaoka, Yutaka, Yamamura, Ken-ichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Research Foundation 2012
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3345944/
https://www.ncbi.nlm.nih.gov/pubmed/22586407
http://dx.doi.org/10.3389/fphys.2012.00126

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3345944/
https://www.ncbi.nlm.nih.gov/pubmed/22586407
http://dx.doi.org/10.3389/fphys.2012.00126

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