Designing cyclopentapeptide inhibitor as potential antiviral drug for dengue virus ns5 methyltransferase

NS5 methyltransferase (Mtase) has a crucial role in the replication of dengue virus. There are two active sites on NS5 Mtase i.e., SAM and RNA-cap binding sites. Inhibition of the NS5 Mtase activity is expected to prevent the propagation of dengue virus. This study was conducted to design cyclic pep...

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Detalles Bibliográficos
Autores principales: Idrus, Syarifuddin, Tambunan, Usman Sumo Friend, Zubaidi, Ahmad Ardilla
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Biomedical Informatics 2012
Materias:
Hypothesis
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3346019/
https://www.ncbi.nlm.nih.gov/pubmed/22570514
http://dx.doi.org/10.6026/97320630008348

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3346019/
https://www.ncbi.nlm.nih.gov/pubmed/22570514
http://dx.doi.org/10.6026/97320630008348

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