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Designing cyclopentapeptide inhibitor as potential antiviral drug for dengue virus ns5 methyltransferase

NS5 methyltransferase (Mtase) has a crucial role in the replication of dengue virus. There are two active sites on NS5 Mtase i.e., SAM and RNA-cap binding sites. Inhibition of the NS5 Mtase activity is expected to prevent the propagation of dengue virus. This study was conducted to design cyclic pep...

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Detalles Bibliográficos
Autores principales:	Idrus, Syarifuddin, Tambunan, Usman Sumo Friend, Zubaidi, Ahmad Ardilla
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Biomedical Informatics 2012
Materias:	Hypothesis
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3346019/ https://www.ncbi.nlm.nih.gov/pubmed/22570514 http://dx.doi.org/10.6026/97320630008348

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