A first-in-man study to evaluate the safety, tolerability, and pharmacokinetics of pasireotide (SOM230), a multireceptor-targeted somatostatin analog, in healthy volunteers

Pasireotide (SOM230) is a multireceptor-targeted somatostatin analog with high binding affinity for four of the five somatostatin receptor subtypes (sst(1,2,3) and sst(5)), and potential clinical activity in several neuroendocrine and oncologic conditions, including acromegaly, Cushing’s disease, an...

Descripción completa

Detalles Bibliográficos
Autores principales: Golor, Georg, Hu, Ke, Ruffin, Matthieu, Buchelt, Alexandra, Bouillaud, Emmanuel, Wang, Yanfeng, Maldonado, Mario
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2012
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3346155/
https://www.ncbi.nlm.nih.gov/pubmed/22573933
http://dx.doi.org/10.2147/DDDT.S29125

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3346155/
https://www.ncbi.nlm.nih.gov/pubmed/22573933
http://dx.doi.org/10.2147/DDDT.S29125

Ejemplares similares