Rationally engineered nanoparticles target multiple myeloma cells, overcome cell-adhesion-mediated drug resistance, and show enhanced efficacy in vivo

In the continuing search for effective cancer treatments, we report the rational engineering of a multifunctional nanoparticle that combines traditional chemotherapy with cell targeting and anti-adhesion functionalities. Very late antigen-4 (VLA-4) mediated adhesion of multiple myeloma (MM) cells to...

Descripción completa

Detalles Bibliográficos
Autores principales: Kiziltepe, T, Ashley, J D, Stefanick, J F, Qi, Y M, Alves, N J, Handlogten, M W, Suckow, M A, Navari, R M, Bilgicer, B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3346680/
https://www.ncbi.nlm.nih.gov/pubmed/22829966
http://dx.doi.org/10.1038/bcj.2012.10

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3346680/
https://www.ncbi.nlm.nih.gov/pubmed/22829966
http://dx.doi.org/10.1038/bcj.2012.10

Ejemplares similares