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γ sulphate PNA (PNA S): Highly Selective DNA Binding Molecule Showing Promising Antigene Activity

Peptide Nucleic Acids (PNAs), nucleic acid analogues showing high stability to enzyme degradation and strong affinity and specificity of binding toward DNA and RNA are widely investigated as tools to interfere in gene expression. Several studies have been focused on PNA analogues with modifications...

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Detalles Bibliográficos
Autores principales: Avitabile, Concetta, Moggio, Loredana, Malgieri, Gaetano, Capasso, Domenica, Di Gaetano, Sonia, Saviano, Michele, Pedone, Carlo, Romanelli, Alessandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3346730/
https://www.ncbi.nlm.nih.gov/pubmed/22586450
http://dx.doi.org/10.1371/journal.pone.0035774