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Generation of NSE-MerCreMer Transgenic Mice with Tamoxifen Inducible Cre Activity in Neurons

To establish a genetic tool for conditional deletion or expression of gene in neurons in a temporally controlled manner, we generated a transgenic mouse (NSE-MerCreMer), which expressed a tamoxifen inducible type of Cre recombinase specifically in neurons. The tamoxifen inducible Cre recombinase (Me...

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Detalles Bibliográficos
Autores principales: Kam, Mandy Ka Man, Lee, King Yiu, Tam, Paul Kwong Hang, Lui, Vincent Chi Hang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3346737/
https://www.ncbi.nlm.nih.gov/pubmed/22586451
http://dx.doi.org/10.1371/journal.pone.0035799